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KHKI-01128

CAT: 0804-HY-162708-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-162708-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KHKI-01128 is a NUAK2 inhibitor, with an IC50 of 0.024 μM. KHKI-01128 exhibits potent anticancer activity against SW480 colorectal cancer cells[1].
UNSPSC
12352211
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/khki-01128.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CC1=CN=C(NC2=CC=C(N3CCN(C)CC3)C(C(F)(F)F)=C2)N=C1NC4=CC=C(N5CCN(C)CC5)C=C4OC
Molecular Formula
C29H34F3N9O
Molecular Weight
581.64
References & Citations
[1]Lee SH, et al. NUAK2 Inhibitors, KHKI-01128 and KHKI-01215, Exhibit Potent Anticancer Activity Against SW480 Colorectal Cancer Cells. Anticancer Res. 2024 Jul;44 (7) :2909-2919.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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