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SB 203580

CAT: 0498-bs-83266C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-83266C-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A potent and selective inhibitor of p38 MAP kinase, IC50=50 and 500 nM for p38 and p38β2 respectively. No other kinases (in a panel of 30) were significantly inhibited including p38γ and δ at 10 μM2. A potent inhibitor of inflammatory cytokine production (IC50=15-25 mg/kg in mice and rats) in animal models of arthritis, bone resorption, endotoxin shock and immune function3.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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