SB-431542

• Background:

  Potent and selective ALK4, ALK5 and ALK7 inhibitor (TGFβ superfamily Type I activin receptor-like kinase) . (ALK5 IC50 = 94 nM) 1,2. Inhibits TGFβ-induced proliferation of human osteosarcoma cells3. Ehances growth and integrity of embryonic stem cell-derived endothelial cells4. A frequently used agent employed in numerous stem cell differentiation protocols5. Cell permeable.

• Conjugation:

  Unconjugated

• Buffer:

  Yellow solid

• Storage Conditions:

  RT