Products for Research Use Only
RegisterLogin

SB-225002

CAT: 0498-bs-82596C-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-82596C-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Potent and selective CXCR2 receptor antagonist (IC50 = 22 nM) . Displays >150-fold selectivity over CXCR1 receptors.1 Induces apoptosis in both wild-type and p53-deficient ovarian cancer cells (OVCA) via p53 activation and by inducing mitotic catastrophe.2 Blocks IL-8-mediated cellular effects such as oxidative stress-induced cellular senescence3 and neutrophil chemotaxis1. Inhibits HIV replication in lymphocytes and macrophages.4 Inhibits endothelial activation and leukocyte recruitment to cerebral microvessels during neuroinflammation.5
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

Related Products

CatalogName
bs-83288C-01SB-216763
bs-83266C-01SB 203580
bs-82623C-01SB-525334
bs-83168C-01SB-366791
bs-82744C-01SB-705498
bs-82496C-01SB-431542
bs-6480C-01SB-3CT
bs-83265C-01SB 202190
bs-6841C-01SB-218078
bs-6870C-01SB-7720770 2HCl

Alternative Products

CatalogName
B3282-25SB-225002
TRC-S154620-100MGSB 225002
TBI2850-25MGSB-225002, CXCR2 antagonist
GTR19153626-01SB-269970, SB 269970
217783SB-277011-A Dihydrochloride (SB277011A, SB 277011A, Dopamine D3 Receptor Antagonist, SB-277011-A, SB-277011A)
366911-01SB 216763 (SB216763, SB-216763, SCHEMBL30251)
BA5664-5SB-649868
BA8268-10SB-435495

Popular Products