Products for Research Use Only

LDN-192960 HCl

CAT: 0498-bs-83043C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83043C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LDN-192960 is a potent inhibitor of Haspin (IC50 = 10 nM), DYRK2 (IC50 = 2 nM), and DYRK3 (IC50 = 19 nM) .1,2 It induced cytotoxicity and growth inhibition in multiple myeloma and triple negative breast cancer cells and triple negative breast cancer mouse allo/xenografts via partial inhibition of 26S proteasome activity.3
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C