LDN-57444

• Background:

  Inhibits ubiquitin C-terminal hydrolase (UCH-L1) (Ki=0.4 M) . Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. Cell permeable.

• Conjugation:

  Unconjugated

• Buffer:

  Yellow solid

• Storage Conditions:

  -20°C