Topotecan HCl

CAT: 0498-bs-83309C-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0498-bs-83309C-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Topotecan HCl is a water-soluble and orally active analog of camptothecin, a DNA topoisomerase I inhibitor.1 Inhibits topoisomerase I in human MCF-7 breast and DU-145 prostate cancer cells, IC50s = 13 and 2 nM respectively.2 Downregulates B-Myb and MycN expression in neuroblastoma cells.3 A clinically useful anticancer agent.
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

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