Products for Research Use Only

Veliparib 2HCl

CAT: 0498-bs-82486C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82486C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent and selective PARP-inhibitor with Ki values of 5.2 nM and 2.9 nM for PARP-1 and PARP-2, respectively.1 Restores sensitivity to DNA alkylator/methylator temozolomide in glioma cells and xenografts2, and enhances radiotherapy sensitivity in endometrial carcinoma cells3. Also improves sensitivity to DNA replication inhibitor cisplatin in human oral carcinoma cells.4
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C