Mitoguazone · 2HCl

• Background:

  Mitoguazone is a potent and reversible inhibitor of S-adenosylmethionine decarboxylase (SAMD or AdoMetDC) .1,2 SAMD is a component of the polyamine-biosynthetic pathway, thus inhibition may lead to changes in polyamine metabolism.3 Mitoguazone has also been shown to inhibit diamine oxidase and induce spermidine/spermine N-acetyltransferase.4,5 Mitoguazone has been looked at as a potential anti-cancer treatment because of it’s ability to inhibit polyamine synthesis.6

• Conjugation:

  Unconjugated

• Buffer:

  White solid

• Storage Conditions:

  -20°C