Mitoguazone · 2HCl

CAT: 0498-bs-82916C-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0498-bs-82916C-01Size:10 mg

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Background

Mitoguazone is a potent and reversible inhibitor of S-adenosylmethionine decarboxylase (SAMD or AdoMetDC) .1,2 SAMD is a component of the polyamine-biosynthetic pathway, thus inhibition may lead to changes in polyamine metabolism.3 Mitoguazone has also been shown to inhibit diamine oxidase and induce spermidine/spermine N-acetyltransferase.4,5 Mitoguazone has been looked at as a potential anti-cancer treatment because of it’s ability to inhibit polyamine synthesis.6

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

-20°C

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Mitoguazone · 2HCl

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