AG-879

• Background :

  Inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor (pp140c-trk) autophosphorylation (IC50 = 10 µM) . No inhibition of EGF, or PDGF receptor phosphorylation at typical working concentrations.

• Conjugation :

  Unconjugated

• Buffer :

  Yellow solid (MP = 223-224°C)

• Storage Conditions :

  -20°C