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Stavudine

CAT: 0498-bs-82147C-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82147C-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Thymidine derivative that acts as an HIV nucleoside reverse transcriptase inhibitor (NRTI) (EC50 = 8.8 nM for HIV-1 replication in human PBMCs) .1,2 Down-modulates P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition.3 Reduces production of IL-18 and caspase-1 and stimulates Aβ-induced autophagy in macrophages.4
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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