Products for Research Use Only

Zebrafish Ppp2ca Antibody / Pp2a alpha

CAT: 0800-RZ1066Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RZ1066Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide. It is localized to chromosome 5. The gene (approximately 30 kbp) is composed of seven exons and six introns. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of protein serine/threonine phosphatase 2A catalytic subunit (PP2AC) is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL
UniProt
Q567Y8
Host
Rabbit
Reactivity
Zebrafish
Immunogen
An E.coli-derived zebrafish Ppp2ca recombinant protein (amino acids M1-L249) was used as the immunogen for the Zebrafish Ppp2ca antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This Zebrafish Ppp2ca antibody is available for research use only.
Storage Conditions
After reconstitution, the Zebrafish Ppp2ca antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Zebrafish Ppp2ca antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE zebrafish retina tissue with Ppp2ca antibody, HRP secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · Q567Y8

Serine/threonine-protein phosphatase

Q567Y8_DANRE · Danio rerio

View on UniProt ↗
Primary accession
Q567Y8
Review status
UniProtKB unreviewed (TrEMBL)
Gene
ppp2caa
Protein existence
2: Evidence at transcript level
Organism
Danio rerio (Zebrafish)
Taxonomy ID
7955
Alternative names
—
EC number
3.1.3.16
Processing
—
Secondary accessions
A9JT81, F6NGK6
Protein keywords

Cellular component

CentromereChromosome

Molecular function

HydrolaseProtein phosphatase

Ligand

ManganeseMetal-binding