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Zebrafish Cdk5 Antibody

CAT: 0800-RZ1087Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RZ1087Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK5, Cyclin-Dependent Kinase 5, is also known as PSSALRE. The p34 (CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle. The PSSALRE expression is in all human tissues and cell lines tested. The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system. To be activated, CDK5 must associate with its regulatory subunit, p35 (CDK5R1) . CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q9DE44
Host
Rabbit
Reactivity
Zebrafish
Immunogen
An E.coli-derived zebrafish Cdk5 recombinant protein (amino acids M1-Q226) was used as the immunogen for the Zebrafish Cdk5 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This Zebrafish Cdk5 antibody is available for research use only.
Storage Conditions
After reconstitution, the Zebrafish Cdk5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Zebrafish Cdk5 antibody should be determined by the researcher.
Image Legend
Western blot analysis of Cdk5 protein using Cdk5 antibody and zebrafish embryo tissue lysate. The predicted molecular weight of Cdk5 is ~33 kDa.

UniProtKB · Q9DE44

Serine/threonine-protein

Q9DE44_DANRE · Danio rerio

View on UniProt ↗
Primary accession
Q9DE44
Review status
UniProtKB unreviewed (TrEMBL)
Gene
cdk5
Protein existence
2: Evidence at transcript level
Organism
Danio rerio (Zebrafish)
Taxonomy ID
7955
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
A0A8M1PBZ5
Protein keywords

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell cycleCell division

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

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