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WCK-5153

CAT: 0804-HY-120366Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120366Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WCK-5153 is a Penicillin-Binding Protein 2 (PBP2) inhibitor with an IC50 of 0.14 μg/ml (for P. aeruginosa PBP2) and acts as a β-lactam enhancer against Pseudomonas aeruginosa. WCK-5153 can be used in studies of multidrug-resistant (MDR) pathogens[1].
CAS Number
1452460-79-5
UNSPSC
12352005
Target
Bacterial; Beta-lactamase; Penicillin-binding protein (PBP)
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/wck-5153.html
Smiles
O=C([C@H]1CCNC1)NNC([C@H]2N(C(N3OS(=O)(O)=O)=O)C[C@H]3CC2)=O
Molecular Formula
C12H19N5O7S
Molecular Weight
377.37
References & Citations
[1]Rajavel M, et al. Structural Characterization of Diazabicyclooctane β-Lactam "Enhancers" in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa. mBio. 2021;12 (1) :e03058-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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