BIBB 515

CAT: 0804-HY-116175-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-116175-01Size:1 mg
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Description
BIBB 515 is a potent, selective and orally active 2,3-oxidosqualene cyclase (OSC) inhibitor with ED50 values of 0.2-0.5 mg/kg and 0.36-33.3 mg/kg in rats and mice (1-5 hours), respectively. BIBB 515 exerts lipid-lowering effect mainly by inhibiting the production of low-density lipoprotein (LDL) [1].
CAS Number
[156635-05-1]
Product Name Alternative
UT-15-d9, UT-15-d7
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bibb-515.html
Purity
99.44
Solubility
DMSO : 2.5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C=C1)Cl)N2CC/C(CC2)=C\C3=CC=C(C=C3)C4=NCCO4
Molecular Formula
C22H21ClN2O2
Molecular Weight
380.87
References & Citations
[1]Eisele B, et al. Effects of a novel 2,3-oxidosqualene cyclase inhibitor on cholesterol biosynthesis and lipid metabolism in vivo. J Lipid Res. 1997 Mar;38 (3) :564-75.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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