Recombinant Human DEFB4

• Background :

  Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. β-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. β-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors; they are released by proteolytic cleavage of a signal sequence.

• Product Name Alternative :

  Beta-Defensin 104; Beta-Defensin 4; BD-4; DEFB-4; hBD-4; Defensin Beta 104; DEFB104A; DEFB104; DEFB4; DEFB104B

• Accession Number :

  Q8WTQ1

• Host :

  E.coli

• Endotoxin :

  <1 EU/µg as determined by LAL test.

• Purity :

  Greater than 95% as determined by reducing SDS-PAGE

• Form :

  Lyophilized

• Reconstitution :

  Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

• Molecular Weight :

  5.99 KDa

• Shipping Conditions :

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

• Storage Conditions :

  Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

• Formulation :

  Lyophilized from a 0.2 μm filtered solution of 20mM PB, 130mM NaCl, pH 7.4.

• Construct :

  Recombinant Human Beta-Defensin 4 is produced by our E.coli expression system and the target gene encoding Glu23-Pro72 is expressed.

• Species :

  Human