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5-Hydroxymethyluracil

CAT: 0804-HY-W004924-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W004924-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
5-Hydroxymethyluracil is a product of oxidative DNA damage. 5-Hydroxymethyluracil can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase.
CAS Number
4433-40-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-_Hydroxymethyl_pyrimidine-2,4_1H,3H_-dione.html
Concentration
10mM
Purity
99.98
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1NC(C(CO)=CN1)=O
Molecular Formula
C5H6N2O3
Molecular Weight
142.11
Precautions
H302, H315, H319, H335
References & Citations
[1]Djuric Z, et al. Quantitation of 5- (hydroxymethyl) uracil in DNA by gas chromatography with mass spectral detection. Chem Res Toxicol. 1991 Nov-Dec;4 (6) :687-91.|[2]Janoušková M, et al. 5- (Hydroxymethyl) uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase. Chem Commun (Camb) . 2017 Dec 12;53 (99) :13253-13255.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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