Dasabuvir (Standard)

Dasabuvir (Standard)

• CAS Number: 1132935-63-7
• UNSPSC Description: Dasabuvir (Standard) is the analytical standard of Dasabuvir. This product is intended for research and analytical applications. Dasabuvir (ABT-333) is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 and 1.8 nM, respectively[1].
• Target Antigen: DNA/RNA Synthesis; HCV
• Type: Reference Standards
• Related Pathways: Anti-infection;Cell Cycle/DNA Damage
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/dasabuvir-standard.html
• Smiles: CS(=O)(NC1=CC=C2C=C(C3=CC(N(C(N4)=O)C=CC4=O)=CC(C(C)(C)C)=C3OC)C=CC2=C1)=O
• Molecular Weight: 493.57
• References & Citations: [1]Kati W, et al. In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor. Antimicrob Agents Chemother. 2015 Mar;59(3):1505-11.
• Shipping Conditions: Room temperature