Dasabuvir

• Target:

  HCV Protease|||DNA/RNA Synthesis

• Related Pathways:

  Microbiology/Virology|||DNA Damage/DNA Repair|||Proteases/Proteasome|||Cell Cycle/Checkpoint

• Purity:

  0.9962

• Bioactivity:

  Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase. Upon administration and intracellular uptake, dasabuvir binds HCV NS5B polymerase, blocking viral RNA synthesis and replication. The HCV NS5B protein is essential for the replication of the HCV RNA genome.

• Smiles:

  COc1c (cc (cc1C (C) (C) C) -n1ccc (=O) [nH]c1=O) -c1ccc2cc (NS (C) (=O) =O) ccc2c1

• Molecular Formula:

  C26H27N3O5S

• Molecular Weight:

  493.57

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1132935-63-7