Dasabuvir

CAT: 0931-MF-0013518-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0013518-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1132935-63-7
Target
HCV Protease|||DNA/RNA Synthesis
Related Pathways
Microbiology/Virology|||DNA Damage/DNA Repair|||Proteases/Proteasome|||Cell Cycle/Checkpoint
Purity
0.9962
Bioactivity
Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase. Upon administration and intracellular uptake, dasabuvir binds HCV NS5B polymerase, blocking viral RNA synthesis and replication. The HCV NS5B protein is essential for the replication of the HCV RNA genome.
Smiles
COc1c(cc(cc1C(C)(C)C)-n1ccc(=O)[nH]c1=O)-c1ccc2cc(NS(C)(=O)=O)ccc2c1
Molecular Formula
C26H27N3O5S
Molecular Weight
493.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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