Dasabuvir sodium

• Target :

  Others|||DNA/RNA Synthesis|||HCV Protease

• Related Pathways :

  Proteases/Proteasome|||Cell Cycle/Checkpoint|||Others|||Microbiology/Virology|||DNA Damage/DNA Repair

• Bioactivity :

  Dasabuvir (ABT-333) sodium is a non-nucleoside hepatitis C virus (HCV) polymerase inhibitor that exhibits inhibition of the RNA-dependent RNA polymerase (RNA polymerase) encoded by the HCV NS5B gene. Dasabuvir sodium inhibited genotype 1a (strain H77) replicon (EC50: 7.7 nM) and 1b (strain Con1) replicon (EC50: 1.8 nM) .

• Smiles :

  [Na+].COc1c(cc(cc1C(C)(C)C)-n1ccc(=O)[nH]c1=O)-c1ccc2cc([N-]S(C)(=O)=O)ccc2c1

• Molecular Formula :

  C26H26N3NaO5S

• Molecular Weight :

  515.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1132940-11-4