UGT1A9 rabbit pAb

• Description:

  This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008],

• Synonyms:

  UDP-glucuronosyltransferase 1-9 (UDPGT 1-9) (UGT1*9) (UGT1-09) (UGT1.9) (EC 2.4.1.17) (UDP-glucuronosyltransferase 1-I) (UGT-1I) (UGT1I) (UDP-glucuronosyltransferase 1A9) (lugP4)

• Gene ID:

  54600

• UniProt:

  O60656

• Cellular Locus:

  Endoplasmic reticulum membrane ; Single-pass membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from human UGT1A9 AA range: 390-440

• Clonality:

  Polyclonal

• Validated Applications:

  WB

• Stability:

  1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000

• Molecular Weight:

  75kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.