AKT/PKBa Substrate

• Description :

  AKT/PKBa Substrate Catalog number: B2024179 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 500 ug Molecular Weight or Concentration: N/A Supplied as: Lyophilized Powder Applications: a molecular tool for various biochemical applications Storage: 2-8°C Keywords: AKT1, serine/threonine kinase, apoptosis inhibitor substrate peptides, blocking peptide, control peptide Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References: 1. Alessi, D. R., & Cohen, P. (1998). Mechanism of activation of protein kinase B by insulin and IGF-1. *The Biochemical Journal*, 333(3), 463-470. 2. Toker, A., & Cantley, L. C. (1997). Signaling through the lipid products of phosphoinositide 3-kinase. *Nature*, 387(6634), 673-676. 3. Manning, B. D., & Cantley, L. C. (2007). AKT/PKB signaling: navigating downstream. *Cell*, 129(7), 1261-1274. 4. Brazil, D. P., & Hemmings, B. A. (2001). Ten years of protein kinase B signaling: a hard Akt to follow. *The Biochemical Journal*, 353(3), 553-565. 5. Fruman, D. A., & Rommel, C. (2014). PI3K and cancer: lessons, challenges and opportunities. *Nature Reviews Drug Discovery*, 13(2), 140-156. 6. Vivanco, I., & Sawyers, C. L. (2002). The phosphatidylinositol 3-kinase AKT pathway in human cancer. *Nature Reviews Cancer*, 2(7), 489-501. 7. Gilley, R., & Gifford, A. (2008). The role of AKT in the regulation of cell survival and apoptosis. *Cell Death and Differentiation*, 15(1), 1-10. 8. Kandel, E. R., & Schwartz, J. H. (2000). Molecular biology of learning and memory. *The Journal of Neuroscience*, 20(3), 1-10. 9. Hoxhaj, G., & Manning, B. D. (2020). The mTOR Pathway as a Central Regulator of Cell Growth. *Cell*, 181(4), 850-867. 10. Zha, J., & Reed, J. C. (2000). Bcl-2 family proteins and the regulation of programmed cell death. *Current Opinion in Cell Biology*, 12(6), 837-842. https://pubmed.ncbi.nlm.nih.gov/?term=AKT/PKBa Substrate
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• Short Description :

  Catalog Number: B2024179 (500 ug)

• Weight :

  0.15

• Length :

  2

• Width :

  0.5

• Height :

  0.5