AKT/PKB/Rac-Protein Kinase Substrate Conjugated to Biotin

• Description:

  _x000D_ AKT/PKB/Rac-Protein Kinase Substrate Conjugated to Biotin_x000D_ Catalog number: B2011229_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 mg_x000D_ Molecular Weight or Concentration: 1942.3 g/mol_x000D_ Supplied as: Lyophilized_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20 °C_x000D_ Keywords: AKT,PKB,Rac-Protein Kinase Substrate_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream Cell. 2007 Jun 29;129(7):1261-74._x000D_ 2: Risso G, Blaustein M, Pozzi B, Mammi P, Srebrow A. Akt/PKB: one kinase, many modifications Biochem J. 2015 Jun 1;468(2):203-14._x000D_ 3: Balasuriya N, Davey NE, Johnson JL, Liu H, Biggar KK, Cantley LC, Li SS, O'Donoghue P. Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1) J Biol Chem. 2020 Jun 12;295(24):8120-8134._x000D_ 4: Ksiezak-Reding H, Pyo HK, Feinstein B, Pasinetti GM. Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro Biochim Biophys Acta. 2003 Nov 20;1639(3):159-68._x000D_ 5: Thapa N, Horn HT, Anderson RA. Phosphoinositide spatially free AKT/PKB activation to all membrane compartments Adv Biol Regul. 2019 May;72:1-6._x000D_ 6: Iida M, Harari PM, Wheeler DL, Toulany M. Targeting AKT/PKB to improve treatment outcomes for solid tumors Mutat Res. 2020 Jan-Apr;819-820:111690._x000D_ 7: Bertacchini J, Beretti F, Cenni V, Guida M, Gibellini F, Mediani L, Marin O, Maraldi NM, de Pol A, Lattanzi G, Cocco L, Marmiroli S. The protein kinase Akt/PKB regulates both prelamin A degradation and Lmna gene expression FASEB J. 2013 Jun;27(6):2145-55._x000D_ 8: Jiang ZY, Zhou QL, Holik J, Patel S, Leszyk J, Coleman K, Chouinard M, Czech MP. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells J Biol Chem. 2005 Jun 3;280(22):21622-8._x000D_ 9: Sasaki K, Sato M, Umezawa Y. Fluorescent indicators for Akt/protein kinase B and dynamics of Akt activity visualized in living cells J Biol Chem. 2003 Aug 15;278(33):30945-51._x000D_ 10: Powell DW, Rane MJ, Chen Q, Singh S, McLeish KR. Identification of 14-3-3zeta as a protein kinase B/Akt substrate J Biol Chem. 2002 Jun 14;277(24):21639-42. _x000D_ _x000D_ Products Related to_x000D_ AKT/PKB/Rac-Protein Kinase Substrate Conjugated to Biotin can be found at Substrates

• Short Description:

  Catalog Number: B2011229 (1 mg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5