Caspase Substrate

• Description:

  Caspase Substrate_x000D_ Catalog number: B2014423_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 2 mg_x000D_ Molecular Weight or Concentration: 754.76 g/mol_x000D_ Supplied as: Powder_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: −20°C_x000D_ Keywords: Caspase Substrate_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Araya LE, Soni IV, Hardy JA, Julien O. Deorphanizing Caspase-3 and Caspase-9 Substrates In and Out of Apoptosis with Deep Substrate Profiling ACS Chem Biol. 2021 Nov 19;16(11):2280-2296._x000D_ 2: McIlwain DR, Berger T, Mak TW. Caspase functions in cell death and disease Cold Spring Harb Perspect Biol. 2013 Apr 1;5(4):a008656._x000D_ 3: Julien O, Wells JA. Caspases and their substrates Cell Death Differ. 2017 Aug;24(8):1380-1389._x000D_ 4: Timmer JC, Salvesen GS. Caspase_substrates Cell Death Differ. 2007 Jan;14(1):66-72._x000D_ 5: Song Y, Song J, Wang M, Wang J, Ma B, Zhang W. Porcine Gasdermin D Is a Substrate of Caspase_1 and an Executioner of Pyroptosis Front Immunol. 2022 Mar 14;13:828911._x000D_ 6: Datta D, McClendon CL, Jacobson MP, Wells JA. Substrate_ and inhibitor-induced dimerization and cooperativity in caspase-1 but not caspase-3 J Biol Chem. 2013 Apr 5;288(14):9971-9981._x000D_ 7: Dagbay KB, Bolik-Coulon N, Savinov SN, Hardy JA. Caspase_6 Undergoes a Distinct Helix-Strand Interconversion upon Substrate Binding J Biol Chem. 2017 Mar 24;292(12):4885-4897._x000D_ 8: Agnew A, Nulty C, Creagh EM. Regulation, Activation and Function of Caspase-11 during Health and Disease Int J Mol Sci. 2021 Feb 3;22(4):1506._x000D_ 9: Salvesen GS, Riedl SJ. Caspase mechanisms Adv Exp Med Biol. 2008;615:13-23._x000D_ 10: Ramirez MLG, Poreba M, Snipas SJ, Groborz K, Drag M, Salvesen GS. Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1 J Biol Chem. 2018 May 4;293(18):7058-7067. _x000D_ _x000D_ Products Related to Caspase Substrate can be found at Substrates

• Short Description:

  Catalog Number: B2014423 (2 mg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5