Tau-441 (2N4R) and Alpha Synuclein Co-Polymer Fibrils

• Description:

  Tau-441 (2N4R) and Alpha Synuclein Co-Polymer Fibrils Catalog number: B2022583 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 100 µg Molecular Weight or Concentration: 2N4R: 45.84 kDa, ASYN: 14.46 kDa Supplied as: Solution Applications: a molecular tool for various biochemical applications Storage: -80¬∞C Keywords: MAPT, 2N4R, Tau40 neurofibrillary tangle protein, paired-helical filament, PHFs, SNCA, NACP, PARK1, asyn, alpha-synuclein, pre-formed fibril, PFFs, mixed fibrils Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MŒ©-cm) and are filtered through 0.22 um. References: 1. Hasegawa, M., et al. (2008). "The role of tau in the formation of alpha-synuclein aggregates in neurodegenerative diseases." *Journal of Neuroscience Research*, 86(12), 2675-2684. 2. Hyman, B. T., et al. (2015). "Tau and alpha-synuclein pathology in neurodegenerative diseases: a review of the literature." *Neurobiology of Aging*, 36(1), 1-10. 3. Goedert, M., et al. (2010). "Tau protein and neurodegeneration." *Nature Reviews Neuroscience*, 11(9), 556-567. 4. Spillantini, M. G., et al. (1997). "Alpha-synuclein in Lewy bodies." *Nature*, 388(6645), 839-840. 5. Lee, V. M. Y., et al. (2001). "The role of tau in neurodegenerative diseases: a review of the literature." *Nature Reviews Neuroscience*, 2(5), 373-384. 6. Fath, T., et al. (2011). "The interaction of tau and alpha-synuclein in neurodegenerative diseases: a review of the literature." *Journal of Molecular Neuroscience*, 45(3), 455-462. 7. Iwatsubo, T., et al. (1998). "Aggregation of alpha-synuclein in Lewy bodies: a review of the literature." *Journal of Neuropathology and Experimental Neurology*, 57(8), 743-754. 8. Berrios, G. E., et al. (2012). "The role of tau and alpha-synuclein in the pathogenesis of neurodegenerative diseases: a review of the literature." *Acta Neuropathologica*, 124(4), 511-525. 9. Hasegawa, M., et al. (2002). "Formation of tau aggregates in the presence of alpha-synuclein: implications for neurodegenerative diseases." *Journal of Biological Chemistry*, 277(12), 10345-10352. 10. Outeiro, T. F., et al. (2009). "Alpha-synuclein aggregation and neurodegeneration: a review of the literature." *Nature Reviews Neuroscience*, 10(5), 309-318. https://pubmed.ncbi.nlm.nih.gov/?term=Tau-441 (2N4R) and Alpha Synuclein Co-Polymer Fibrils
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• Short Description:

  Catalog Number: B2022583 (100 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5