Debio-0123

CAT: 1410-M37689-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M37689-01Size:1 g
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Debio-0123 (WEE1-IN-5) is a potent, orally available and highly specific WEE1 inhibitor with an IC 50 in the low nanomolar range. Debio-0123 inhibits phospho-CDC2 which translated into an increase in DNA damage and premature entry into mitosis. Debio-0123 increases the antitumoral activity of Carboplatin in vivo whereas neither agent was active alone .
CAS Number
2243882-74-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
511.45
Molecular Formula
C26H28Cl2N6O
Notes
Research use only, not for human use.
Receptor
Wee1

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