Debio-0123

• Description:

  Debio-0123 (WEE1-IN-5) is a potent, orally available and highly specific WEE1 inhibitor with an IC 50 in the low nanomolar range. Debio-0123 inhibits phospho-CDC2 which translated into an increase in DNA damage and premature entry into mitosis. Debio-0123 increases the antitumoral activity of Carboplatin in vivo whereas neither agent was active alone .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  511.45

• Molecular Formula:

  C26H28Cl2N6O

• Notes:

  Research use only, not for human use.

• Receptor:

  Wee1

• CAS Number:

  2243882-74-6