DEBIO 1143

• Description:

  DEBIO 1143 (AT-406, DEBIO-1143, SM406, ARRY-334543, D1143) is potent, orally active Smac mimetic that antagonizes cIAP1, cIAP2 and XIAP with Ki of 66.4, 1.9 and 5.1 nM, respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  561.727

• Molecular Formula:

  C32H43N5O4

• Notes:

  Research use only, not for human use.

• Receptor:

  CIAP1-BIR3|cIAP2-BIR3|XIAP-BIR3

• CAS Number:

  1071992-99-8