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PD-L1-IN-3

CAT: 1410-M37233-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M37233-01Size:1 Each
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Description
PD-L1-IN-3 (Compound 4a) functions as an inhibitor of the PD-1/PD-L1 axis, with an IC50 value of 4.97 nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1 interaction by binding to the PD-L1 dimer, obstructing PD-1 signaling. This compound is utilized in research pertaining to lung cancer and melanoma .
CAS Number
2953044-29-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
373.85
Molecular Formula
C19H15ClFN2OS
Notes
Research use only, not for human use.
Receptor
PD-1/PD-L1

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