PD-L1-IN-3

• Description:

  PD-L1-IN-3 (Compound 4a) functions as an inhibitor of the PD-1/PD-L1 axis, with an IC50 value of 4.97 nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1 interaction by binding to the PD-L1 dimer, obstructing PD-1 signaling. This compound is utilized in research pertaining to lung cancer and melanoma .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  373.85

• Molecular Formula:

  C19H15ClFN2OS

• Notes:

  Research use only, not for human use.

• Receptor:

  PD-1/PD-L1

• CAS Number:

  2953044-29-4