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NRX-252114 B

CAT: 1410-M35723-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M35723-01Size:1 g
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Description
NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM.
CAS Number
2763260-39-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
510.32
Molecular Formula
C22H12Cl2F3N3O2S
Notes
Research use only, not for human use.
Receptor
Wnt/beta-catenin

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