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NRX-103094

CAT: 0931-T63427-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T63427-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2763260-36-0
Target
Molecular Glues, Wnt/beta-catenin
Related Pathways
PROTAC, Cytoskeletal Signaling, Stem Cells
Purity
0.995
Bioactivity
NRX-103094 is a potent enhancer of the interaction between β-catenin and the homologous E3 ligase SCFβ-TrCP, increasing the affinity of pSer33/Ser37 β-catenin for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM.
Smiles
S(C1=C(C(NC2=CC(C(O)=O)=CC=C2)=O)C(=O)NC(C(F)(F)F)=C1)C3=C(Cl)C=CC=C3Cl
Molecular Formula
C20H11Cl2F3N2O4S
Molecular Weight
503.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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