APTO-253

• Description :

  APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.APTO-253 (5 μM) induces KLF4 expression and enhances apoptosis induced by NSC 119875 in both SKOV3 and OVCAR3 cells.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  367.38

• Molecular Formula :

  C22H14FN5

• Notes :

  Research use only, not for human use.

• Receptor :

  C-Myc

• CAS Number :

  916151-99-0