AC 253

• Description :

  Amylin (AMY3) receptor antagonist. Inhibits andrenomedulin-stimulated cAMP production in vitro. Protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. Blocks electrophysiological effects of Aβ in vitro. Cyclic AC 253 also available.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  2847.11

• Molecular Formula :

  C122H196N40O39

• Notes :

  Research use only, not for human use.

• Receptor :

  ——

• CAS Number :

  151804-79-4