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FG 7142

CAT: 1410-M22444-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M22444-02Size:1 mL x 10 mM in DMSO
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Description
FG 7142 also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM) . FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM) .
CAS Number
78538-74-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
225.25
Molecular Formula
C13H11N3O
Notes
Research use only, not for human use.
Receptor
GABAA receptor

Chemical Information

FG-7142

N-methyl-9H-pyrido[3,4-b]indole-3-carboxamide is a member of beta-carbolines.

CAS Number78538-74-6
PubChem CID4375
IUPAC NameN-methyl-9H-pyrido[3,4-b]indole-3-carboxamide
Molecular FormulaC13H11N3O
Molecular Weight225.25
XLogP2.8
Topological Polar Surface Area57.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count17
Formal Charge0
Complexity307
SMILES
CNC(=O)C1=NC=C2C(=C1)C3=CC=CC=C3N2
InChI
InChI=1S/C13H11N3O/c1-14-13(17)11-6-9-8-4-2-3-5-10(8)16-12(9)7-15-11/h2-7,16H,1H3,(H,14,17)
InChIKey
QMCOPDWHWYSJSA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of FG-7142
CAS: 78538-74-6
CID: 4375
Formula: C13H11N3O
MW: 225.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight225.25
XLogP32.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass225.090211983
Monoisotopic Mass225.090211983
Topological Polar Surface Area57.8 Ų
Heavy Atom Count17
Formal Charge0
Complexity307
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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