FG 7142

• Description:

  FG 7142 also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM) . FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  225.25

• Molecular Formula:

  C13H11N3O

• Notes:

  Research use only, not for human use.

• Receptor:

  GABAA receptor

• CAS Number:

  78538-74-6