Dolphin IL-2 ELISpot

• Background:

  IL-2 is produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. IL-2 was discovered to be a member of a family of cytokines, which also includes IL-4, IL-7, IL-9, IL-15 and IL-21. IL-2 signals through a receptor complex consisting of IL-2 specific IL-2 receptor alpha (CD25), IL-2 receptor beta (CD122) and a common gamma chain (γc) . All members of this family use the common gamma chain as part of their signaling complex.

• Description:

  Dolphin IL-2 ELISpot contains Capture Antibody, Standard Control, and Detection Antibody for development of up to two (2) ELISpot assays. Other required materials and reagents are not supplied. The antibodies have been determined to function in an ELISpot with the Standard Control provided. Components may also be purchased separately. For research use only.

• Applications:

  ELISpot

• Homology:

  Globicephala melas (long-finned pilot whale), Orcinus orca (killer whale), Phocoena sinus (vaquita), Tursiops truncatus (common bottlenose dolphin)

• Storage Temperature:

  2°C to 8°C