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Dolphin IL-10 ELISpot

CAT: 0908-SPOT2415PSize: 1 SetDry Ice: NoHazardous: No
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CAT#:0908-SPOT2415PSize:1 Set
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-10 has multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28A, IL-28B, and IL-29. These cytokines elicit diverse host defense mechanisms. IL-10 family cytokines are essential for maintaining the integrity and homeostasis of tissue epithelial layers. By promoting inamte immune response, members of this family can limit the damage caused by viral and bacterial infections. They can also facilitate the tissue-healing process in injuries caused by infection or inflammation. IL-10 itself is an anti-inflammatory cytokine. IL-10 family cytokines have indispensable functions in many infectious and inflammatory diseases.
Description
Dolphin IL-10 ELISpot contains Capture Antibody, Standard Control, and Detection Antibody for development of up to two (2) ELISpot assays. Other required materials and reagents are not supplied. The antibodies have been determined to function in an ELISpot with the Standard Control provided. Components may also be purchased separately. For research use only.
Applications
ELISpot
Homology
Tursiops truncatus (common bottlenose dolphin)
Storage Temperature
2°C to 8°C

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