Human EGF Polyclonal Antibody

CAT: 0908-KP1471H-01Size: 20 µgDry Ice: NoHazardous: No
CAT#:0908-KP1471H-01Size:20 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EGF (Epidermal Growth Factor) is best known for having the ability to stimulate cell growth and proliferation. There are many EGF responses and they are regulated by seven ligands: EGF, transforming growth factor-alpha (TGFA), heparin-binding EGF-like growth factor (HBEGF), betacellulin (BTC), amphiregulin (AREG), epiregulin (EREG), and epigen (EPGN) and four ErbB (HER) family receptor tyrosine kinases: EGFR/ErbB1, ErbB2, ErbB3 and ErbB4. EGF family members are important for development and promoting mitogenesis and differentiation of mesenchymal and epithelial cells. EGF acts as a mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. EGF plays a significant role in epithelial development, angiogenesis, regulation of gastric acid secretion, fibroblast proliferation, and colony formation of epidermal cells in culture. EGF dysregulation is also associated with the growth and progression of many cancers.
Description
The Human EGF polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Human EGF ELISA. The Human EGF antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Canine EGF - None) (Chicken EGF - None) (Human EGF - Strong) (Feline EGF - None) (Mouse EGF - None) (Swine EGF - None) . For research use only.
Host
Rabbit
Label
Unconjugated
Applications
ELISA, ELISpot, Flow Cytometry, Neutralization, Western Blot
Purification
Antigen-affinity
Homology
Gorilla gorilla gorilla (western lowland gorilla), Homo sapiens (human), Pan paniscus (pygmy chimpanzee), Pan troglodytes (chimpanzee)
Storage Temperature
2°C to 8°C
Scientific Category
Antibody

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