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SMAL1 rabbit pAb

CAT: 0855-ES13062-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES13062-01Size:50 µL
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Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. [provided by RefSeq, Jul 2008],
Product Name Alternative
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (hHARP) (Sucrose nonfermenting protein 2-like 1)
UniProt
Q9NZC9
Swiss Prot
Q9NZC9
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human SMAL1 AA range: 485-535
Target
SMAL1
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
105kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
105kD
Fragment
IgG
Subcellular Location
Nucleus . Recruited to damaged DNA regions.
Other Product Names
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (hHARP) (Sucrose nonfermenting protein 2-like 1)
Gene ID (Human)
50485

UniProtKB · Q9NZC9

SNF2 related chromatin remodeling annealing helicase 1

SMAL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NZC9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SMARCAL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.4.-, 5.6.2.-
Processing
—
Secondary accessions
A6NEH0, Q53R00, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Domain

Coiled coilRepeat

Disease

Disease variant

Molecular function

HydrolaseIsomerase

Cellular component

Nucleus

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