PDK4-IN-1 (hydrochloride)
CAT:
804-HY-135954A-03
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PDK4-IN-1 (hydrochloride)
- CAS Number: 2310262-11-2
- UNSPSC Description: PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 hydrochloride potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 hydrochloride has antidiabetic, anticancer and anti-allergic activity[1].
- Target Antigen: Apoptosis; PDHK
- Type: Reference compound
- Related Pathways: Apoptosis;Metabolic Enzyme/Protease
- Field of Research: Cancer; Metabolic Disease; Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/pdk4-in-1-hydrochloride.html
- Smiles: [H]Cl.O=C1C2=C(C=CC=C2)C(C3=CC=CC(C4=CN(C5CCNCC5)N=C4)=C13)=O
- Molecular Weight: 393.87
- References & Citations: [1]Lee D, et al. Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases. J Med Chem. 2019 Jan 24;62(2):575-588.
- Shipping Conditions: Room Temperature