HV1-IN-1 (hydrochloride)

HV1-IN-1 (hydrochloride)

• CAS Number: 1609461-57-5
• UNSPSC Description: HV1-IN-1 hydrochloride is an inhibitor of the human voltage-gated proton channel (hHV1). HV1-IN-1 hydrochloride works by binding to the VSD of the HV1 channel. The VSD is a component of the HV1 channel that is responsible for detecting changes in membrane potential and triggering the opening of the channel. HV1-IN-1 hydrochloride can be used in the study of cancer, neuroinflammation and immune response[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Cancer; Neurological Disease; Others
• Assay Protocol: https://www.medchemexpress.com/hv1-in-1-hydrochloride.html
• Smiles: NC1=NC=C(N1)C2=CC=CC(NC(C3=CC4=C(C=CC(OC(F)(F)F)=C4)N3)=O)=C2.Cl
• Molecular Weight: 437.80
• References & Citations: [1]Piga M, et al. Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening[J]. Journal of Chemical Information and Modeling, 2024.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported