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MIP-4 (CCL18)

CAT: 0209-100-080-L1000Size: 1000 µgDry Ice: NoHazardous: No
CAT#:0209-100-080-L1000Size:1000 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MIP-4 is a CC chemokine that is expressed in lymph nodes, lungs, placenta and bone marrow. MIP-4’s primary receptor is unknown. MIP-4 chemoattracts lymphocytes, and has been shown to exert activity on both CD4+and CD8+ T cells. Recombinant human MIP-4 is a 7.8 kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Synonyms
Macrophage Inflammatory Protein-4, CCL18, PARC, DC-CK1, AMAC-1
NCBI Gene ID
6362
UniProt
P55774
Accession Number
NP_002979
Accession Number mRNA
NM_002988
Chromosomal Location
17q11.2
Reactivity
Human
Cross Reactivity
Human, Mouse, Bacteria
Sequence
QVGTNKELC CLVYTSWQIP QKFLVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Assay #1: Determined by its ability to chemoattract human T lymphocytes using a concentration of 1.0 - 10.0 ng/ml. Assay #2: Determined by its ability to chemoattract human iDCs using a concentration of 1.0 - 10.0 ng/ml.
Length
68
Form
Lyophilized
Reconstitution
Water
Molecular Weight
7.8 kDa
Storage Conditions
For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1 % HSA or 0.1% BSA) and store in working aliquots at -20°C to -80°C. Lyophilized MIP-4 although stable at room temperature for 3 weeks, should be stored desiccated below -20°C. Upon reconstitution MIP-4 can be stored at 4°C between 2-7 days and for future use below -20°C.
Host or Source
E. coli

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