IL-13

• Description:

  Interleukin-13 is an immunoregulatory protein produced by activated T-lymphocytes. The biological activities of IL-13 include the stimulation of B cell proliferation and immunoglobulins production. Recombinant Human IL-13 is a 12.5 kDa protein containing 114 amino acid residues.

• Synonyms:

  IL13; ALRH; BHR1; P600; IL-13

• NCBI Gene ID:

  3596

• UniProt:

  P35225

• Accession Number:

  NP_002179.2

• Accession Number mRNA:

  NM_002188

• Chromosomal Location:

  5q31

• Reactivity:

  Human

• Cross Reactivity:

  Mouse, Human, Monkey, Pig, Leech

• Sequence:

  MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.

• Length:

  115

• Form:

  Lyophilized

• Molecular Weight:

  12.6 kDa

• Host or Source:

  E. coli