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ICAM-2 / CD102 Protein

CAT: 0209-M60-104-L100Size: 100 µgDry Ice: YesHazardous: No
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CAT#:0209-M60-104-L100Size:100 µg
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Description
Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) . As the second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity, and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relationship with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in the diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
Synonyms
CD102 Protein; Icam-2 Protein; Icam2 Protein; Ly-60 Protein
Accession Number
NP_034624.1
Reactivity
Mouse
Cross Reactivity
Mouse
Assay Protocol
See Datasheet send with the product
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 95 % as determined by SDS-PAGE
Bioactivity
Data not available
Length
210
Form
Lyophilized
Buffer
PBS, pH 7.4
Reconstitution
See Datasheet
Molecular Weight
40 kDa (glycosylated)
Storage Conditions
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Host or Source
HEK 293 cells

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Alternative Products

CatalogName
ATGP2645-020Recombinant human ICAM-2/CD102 protein
PKSM040565Recombinant Mouse ICAM-2/CD102 Protein
MBS2546867-01Recombinant Mouse ICAM-2 / CD102 Protein
TMPY-03533-01ICAM-2/CD102 Protein, Mouse, Recombinant
P515773ICAM-2; CD102 Protein (C-His, Human)
P515769ICAM-2/CD102 Protein (C-hFc, Mouse)
P515770ICAM-2/CD102 Protein (C-His, Human)
TMPY-01799-01ICAM-2/CD102 Protein, Mouse, Recombinant (hFc)
TMPY-01418-01ICAM-2/CD102 Protein, Human, Recombinant (His)
P515772ICAM-2; CD102 Protein (C-Fc, Mouse)

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