CD102

• Description:

  Intercellular adhesion molecule 2 (ICAM-2), also known as CD102, is a member of the immunoglobulin superfamily and binds the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) . ICAM-2 is constitutively expressed at high levels on vascular endothelial cells and lymphohematopoietic cells. ICAM-2 mediated adhesion has been shown to provide a co-stimulatory signal for T cell aggregation, NK cytotoxicity and NK cell migration.

• Synonyms:

  ICAM2; CD102

• NCBI Gene ID:

  3384

• UniProt:

  P13598

• Accession Number:

  NP_001093256.1

• Accession Number mRNA:

  NM_001099786.1

• Chromosomal Location:

  17q23-q25

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Human recombinant CD102 EC domain

• Clone:

  (#7L4)

• Applications:

  WB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1