I-309 (CCL1)

• Description:

  Human I-309 is an 8.5 kDa protein containing 74 amino acid residues. I-309 is a small glycoprotein secreted by activated T lymphocytes and structurally related to other CC chemokines.

• Synonyms:

  CCL1; P500; SISe; TCA3; I-309; SCYA1

• NCBI Gene ID:

  6346

• UniProt:

  P22362

• Accession Number:

  NP_002972.1

• Accession Number mRNA:

  NM_002981

• Chromosomal Location:

  17q12

• Reactivity:

  Human

• Cross Reactivity:

  Mouse, Human

• Sequence:

  SKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKRGKEA CALDTVGWVQ RHRKMLRHCP SKRK

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Determined by its ability to chemoattract human monocytes using a concentration range of 10-30 ng/ml.

• Length:

  74

• Form:

  Lyophilized

• Molecular Weight:

  8.5 kDa

• Host or Source:

  E. coli