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HGF Recombinant Protein

CAT: 0223-40-580-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0223-40-580-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Murine HGF is expressed as a linear 728 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (α -chain and β -chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α -chain consists of 463 amino acid residues and four kringle domains. The β -chain consists of 233 amino acid residues.*Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
NCBI Gene ID
15234
Swiss Prot
Q08048
Accession Number
NP_001276387.1
Type
Recombinant Proteins
Source
(BTI-Tn-5B1-4) High-5 Insect cells
Purity
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized HGF recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted HGF stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing HGF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Hepatocyte growth factor
NCBI Organism
Mus musculus
Other Product Names
SF, NK1, NK2, HGF/SF, SF/HGF, C230052L06Rik, Hepatocyte growth factor, Hepatopoietin-A, SF
Species
Murine
Protein ID
575501559
Physical Properties
Lyophilized

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