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BMP-3 Recombinant Protein

CAT: 0223-40-547-01Size: 0.01 mgDry Ice: NoHazardous: No
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CAT#:0223-40-547-01Size:0.01 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-3 is abundantly found in adult bone, and to a lesser extent fetal cartilage. BMP-3 inhibits osteogenesis and bone formation by activating a signaling cascade that antagonizes the signaling of pro-osteogenic BMPs. Recombinant human BMP-3 is a disulfide linked homodimeric protein that corresponds to residues 361 to 472 of the 472 amino acid BMP-3 precursor protein.
NCBI Gene ID
651
Swiss Prot
P12645
Accession Number
NP_001192.2
Type
Recombinant Proteins
Source
E. coli
Field of Research
Growth Factors, Signal Transduction
Purity
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized BMP-3 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted BMP-3 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing BMP-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Bone morphogenetic protein 3
NCBI Organism
Homo sapiens
Other Product Names
BMP-3A, BMP3A, Bone morphogenetic protein 3, Bone morphogenetic protein 3A, BMP-3
Species
Human
Protein ID
126507087
Physical Properties
Lyophilized

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