BMP-5 Recombinant Protein

• Background:

  TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lung and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant human BMP-5 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.

• NCBI Gene ID:

  653

• Swiss Prot:

  P22003

• Accession Number:

  NP_066551.1

• Type:

  Recombinant Proteins

• Source:

  CHO cells

• Field of Research:

  Cell Cycle, Growth Factors, Signal Transduction, Stem Cell

• Purity:

  Greater than 95% by SDS-PAGE gel and HPLC analyses.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized BMP-5 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted BMP-5 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing BMP-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Bone morphogenetic protein 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Bone morphogenetic protein 5, BMP-5

• Species:

  Human

• Protein ID:

  10835091

• Physical Properties:

  Lyophilized