BMP-4 Recombinant Protein

• Background:

  Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. ProSci’s E.coli derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.

• NCBI Gene ID:

  652

• Swiss Prot:

  P12644

• Accession Number:

  NP_001193.2

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Growth Factors, Signal Transduction, Stem Cell, Other

• Purity:

  Greater than 98% by SDS-PAGE gel and HPLC analyses.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized BMP-4 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted BMP-4 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing BMP-4 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Bone morphogenetic protein 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, DVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP-4

• Species:

  Human

• Protein ID:

  157276593

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3