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TNF alpha Recombinant Protein

CAT: 0223-40-446-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0223-40-446-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TNF-alpha is a pleiotrophic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant murine TNF-alpha is a soluble 156 amino acid protein (17.3 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.
NCBI Gene ID
21926
Swiss Prot
P06804
Accession Number
NP_001265530.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Chemokines & Cytokines, Growth Factors, Immunology, Signal Transduction
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized TNF alpha recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TNF alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TNF alpha recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Tumor necrosis factor
NCBI Organism
Mus musculus
Other Product Names
DIF, Tnfa, TNF-a, TNFSF2, Tnfsf1a, TNFalpha, TNF-alpha, Tnfsf2, Tumor necrosis factor, Cachectin
Species
Murine
Protein ID
518831589
Physical Properties
Lyophilized

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